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Listar por autor "Lucas Rodríguez, Ricardo"
Mostrando ítems 1-20 de 28
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Artículo
Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: Relevance of their surface active properties and of the type of emulsifier
González, M. Jesús; Medina, Isabel; Maldonado, Olivia S.; Lucas Rodríguez, Ricardo; Morales, Juan C. (Elsevier, 2015)The antioxidant activity of gallic acid and a series of alkyl gallates (C4-C18) and glycosylated alkyl gallates (C4-C18) ...
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Apolar carbohydrates as DNA capping agents
Lucas Rodríguez, Ricardo; Vengut Climent, Empar; Gómez Pinto, Irene; Aviñó, Anna; Eritja, Ramón; González, Carlos; Morales, Juan Carlos (Royal Society of Chemistry, 2012)Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. ...
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Carbohydrate-DNA interactions at G-quadruplexes: Folding and stability changes by attaching sugars at the 5′-End
Gómez Pinto, Irene; Vengut Climent, Empar; Lucas Rodríguez, Ricardo; Aviñó, Anna; Eritja, Ramón; González, Carlos; Morales, Juan Carlos (Wiley-Blackwell, 2013)Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry, ranging from chemical biology, ...
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Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites
Falomir, Eva; Lucas Rodríguez, Ricardo; Peñalver, Pablo; Martí Centelles, Rosa; Dupont, Alexia; Zafra-Gómez, Alberto; Carda, Miguel; Morales, Juan C. (Wiley-Blackwell, 2016)Resveratrol (RES) is a natural polyphenol with relevant and varied biological activity. However, its low bioavailability ...
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Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
López Martín, Sergio; Montserrat de la Paz, Sergio; Lucas Rodríguez, Ricardo; Bermúdez Pulgarín, Beatriz; Abia González, María del Rocío; Morales, Juan C.; García Muriana, Francisco José (Elsevier, 2017)The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ...
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Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
Lucas Rodríguez, Ricardo; Peñalver, Pablo; Gomez Pinto, Irene; Vengut Climent, Empar; Matashobya, L.; Cousin, J.; Sanchez Maldonado, Olivia; Reynes, Virginie; Aviñó, Anna; Eritja Casadellà, Ramón; González, Carlos; Linclau, Bruno; Morales, Juan C. (American Chemical Society, 2014)Carbohydrate–aromatic interactions are highly relevant for many biological processes. Nevertheless, experimental data in ...
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Trabajo Fin de Grado
¿Está presente la diversidad familiar en el aula?
Donoso Ruiz-Castizo, Leonardo (2018)El siguiente trabajo de fin de grado pretende la visión, tanto de docentes como del alumnado, del tercer ciclo de Educación ...
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Trabajo Fin de Grado
El fútbol como medio para la inclusión social en Educación Primaria
Ramírez Ramos, Lucía (2020)Para este trabajo de Fin de Grado se ha realizado un estudio sobre el deporte, más concretamente, sobre la inclusión ...
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Glucose-nucleobase pairs within DNA: Impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
Vengut Climent, Empar; Peñalver, Pablo; Lucas Rodríguez, Ricardo; Gómez Pinto, Irene; Aviñó, Anna; Muro Pastor, Alicia María; Galbis Fuster, Elsa; Paz Báñez, María Violante de; Fonseca Guerra, Célia; Bickelhaupt, F. Matthias; Eritja, Ramón; González, Carlos; Morales, Juan Carlos (Royal Society of Chemistry, 2018)Recently, we studied glucose-nucleobase pairs, a binding motif found in aminoglycoside-RNA recognition. DNA duplexes with ...
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Glucose–Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
Vengut Climent, Empar; Gómez Pinto, Irene; Lucas Rodríguez, Ricardo; Peñalver, Pablo; Aviñó, Anna; Fonseca Guerra, Célia; Bickelhaupt, F. Matthias; Eritja, Ramón; González, Carlos; Morales, Juan C. (Wiley-Blackwell, 2016)Noncovalent forces rule the interactions between biomolecules. Inspired by a biomolecular interaction found in aminoglycoside–RNA ...
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Highly Polar Carbohydrates Stack Onto DNA Duplexes Via CH/π Interactions
Lucas Rodríguez, Ricardo; Gómez Pinto, Irene; Aviñó, Anna; Reina, Jose J.; Eritja, Ramón; González, Carlos; Morales, Juan C. (American Chemical Society, 2011)Carbohydrate-nucleic acid contacts are known to be a fundamental part of some drug-DNA recognition processes. Most of these ...
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Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells
Atzeri, Angela; Lucas Rodríguez, Ricardo; Incani, Alessandra; Peñalver, Pablo; Zafra-Gómez, Alberto; Melis, M. Paola; Pizzala, Roberto; Morales, Juan C.; Deiana, Monica (Royal Society of Chemistry, 2016)The aim of this study was to investigate the ability of the sulfate metabolites of hydroxytyrosol (HT) and tyrosol (TYR) ...
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In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations
Iglesias Blanco, Nieves; Galbis Fuster, Elsa; Romero Azogil, Lucía; Benito Hernández, Elena María; García Martín, María de Gracia; Lucas Rodríguez, Ricardo; Paz Báñez, María Violante de (MDPI, 2020)The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. ...
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Metabolites and tissue distribution of resveratrol in the pig
Azorín-Ortuño, María; Yáñez-Gascón, María J.; Vallejo, Fernando; Pallarés, Francisco J.; Larrosa, Mar; Lucas Rodríguez, Ricardo; Morales, Juan C.; Tomás-Barberán, Francisco A.; García-Conesa, María T.; Espín, Juan C. (Wiley-Blackwell, 2011-08)Scope: trans-Resveratrol (RES) and/(or) its metabolites exert many effects in vivo. Our aim was to study the metabolism ...
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Nanostructured Chitosan-Based Biomaterials for Sustained and Colon-Specific Resveratrol Release
Iglesias, N.; Galbis Fuster, Elsa; Díaz Blanco, Manuel Jesús; Lucas Rodríguez, Ricardo; Benito Hernández, Elena María; Paz Báñez, María Violante de (MDPI, 2019-01)In the present work, we demonstrate the preparation of chitosan-based composites as vehicles of the natural occurring ...
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Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells
Peñalver, Pablo; Zodio, Sonia; Lucas Rodríguez, Ricardo; Paz Báñez, María Violante de; Morales, Juan Carlos (American Chemical Society, 2020)Oxidative stress is known to be a key factor in many neurodegenerative diseases. Inflammation also plays a relevant role ...
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pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems
Galbis Fuster, Elsa; Paz Báñez, María Violante de; Iglesias, N.; Lucas Rodríguez, Ricardo; Galbis Pérez, Juan Antonio (JSciMed Central, 2017-04)Micelles are excellent devices to be used as controlled drug delivery systems since they exhibit the ability to protect ...
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Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents
Larrosa, Mar; Tomé-Carneiro, Joao; Yáñez-Gascón, María J.; Alcántara, David; Selma, María V.; Beltrán, David; García-Conesa, María T.; Urbán, Cristina; Lucas Rodríguez, Ricardo; Tomás-Barberán, Francisco; Morales, Juan C.; Espín, Juan Carlos (American Chemical Society, 2010-10-28)There is no pharmaceutical or definitive surgical cure for inflammatory bowel diseases (IBDs). The naturally occurring ...
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Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines
Selma, María V.; Larrosa, Mar; Beltrán, David; Lucas Rodríguez, Ricardo; Morales, Juan C.; Tomás-Barberán, Francisco; Espín, Juan C. (American Chemical Society, 2012)The efficacy of resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives in inhibiting the adhesion of ...
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Artículo
Surface-Active Properties of Lipophilic AntioxidantsTyrosol and Hydroxytyrosol Fatty Acid Esters: A PotentialExplanation for the Nonlinear Hypothesis of the AntioxidantActivity in Oil-in-Water Emulsions
Lucas Rodríguez, Ricardo; Comelles, Francisco; Alcántara, David; Maldonado, Olivia S.; Curcuroze, Melanie; Parra, Jose L.; Morales, Juan C. (American Chemical Society, 2001)Our group has recently observed a nonlinear tendency in antioxidant capacity of different hydroxytyrosol fatty acid esters ...